Structure of a novel 13 nm dodecahedral nanocage assembled from a redesigned bacterial microcompartment shell protein.
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ABSTRACT:
SUBMITTER: Jorda J
PROVIDER: S-EPMC5081076 | biostudies-literature | 2016 Apr
REPOSITORIES: biostudies-literature
Publications
Structure of a novel 13 nm dodecahedral nanocage assembled from a redesigned bacterial microcompartment shell protein.
Jorda J J Leibly D J DJ Thompson M C MC Yeates T O TO
Chemical communications (Cambridge, England) 20160318 28
We report the crystal structure of a novel 60-subunit dodecahedral cage that results from self-assembly of a re-engineered version of a natural protein (PduA) from the Pdu microcompartment shell. Biophysical data illustrate the dependence of assembly on solution conditions, opening up new applications in microcompartment studies and nanotechnology. ...[more]
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