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Chronic multiscale imaging of neuronal activity in the awake common marmoset.

ABSTRACT: We report a methodology to chronically record in vivo brain activity in the awake common marmoset. Over a month, stable imaging revealed macroscopic sensory maps in the somatosensory cortex and their underlying cellular activity with a high signal-to-noise ratio in the awake but not anesthetized state. This methodology is applicable to other brain regions, and will be useful for studying cortical activity and plasticity in marmosets during learning, development, and in neurological disorders.

SUBMITTER: Yamada Y

PROVIDER: S-EPMC5082371 | biostudies-literature | 2016 Oct

REPOSITORIES: biostudies-literature

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Chronic multiscale imaging of neuronal activity in the awake common marmoset.

Yamada Yoshiyuki Y Matsumoto Yoshifumi Y Okahara Norio N Mikoshiba Katsuhiko K

Scientific reports 20161027

We report a methodology to chronically record in vivo brain activity in the awake common marmoset. Over a month, stable imaging revealed macroscopic sensory maps in the somatosensory cortex and their underlying cellular activity with a high signal-to-noise ratio in the awake but not anesthetized state. This methodology is applicable to other brain regions, and will be useful for studying cortical activity and plasticity in marmosets during learning, development, and in neurological disorders. ...[more]

PMID: 27786241

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