Ontology highlight
ABSTRACT:
SUBMITTER: Ujisawa T
PROVIDER: S-EPMC5082853 | biostudies-literature | 2016
REPOSITORIES: biostudies-literature
PloS one 20161027 10
Temperature sensation by the nervous system is essential for life and proliferation of animals. The molecular-physiological mechanisms underlying temperature signaling have not been fully elucidated. We show here that diverse regulatory machinery underlies temperature sensation through trimeric G-protein signaling in the nematode Caenorhabditis elegans. Molecular-genetic studies demonstrated that cold tolerance is regulated by additive functions of three Gα proteins in a temperature-sensing neur ...[more]