Ontology highlight
ABSTRACT:
SUBMITTER: Zemljic Jokhadar S
PROVIDER: S-EPMC5082891 | biostudies-literature | 2016
REPOSITORIES: biostudies-literature
Zemljič Jokhadar Špela Š Božič Bojan B Kristanc Luka L Gomišček Gregor G
PloS one 20161027 10
The responses of Chinese hamster ovary epithelial cells, caused by the pore-forming agent nystatin, were investigated using brightfield and fluorescence microscopy. Different phenomena, i.e., the detachment of cells, the formation of blebs, the occurrence of "cell-vesicles" and cell ruptures, were observed. These phenomena were compared to those discovered in giant lipid vesicles. A theoretical model, based on the osmotic effects that occur due to the size-discriminating nystatin transmembrane p ...[more]