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Correlates of disease-specific knowledge among patients with chronic hepatitis B or hepatitis C infection in India.

ABSTRACT:

Background

Patient knowledge about chronic diseases increases health-promoting behaviors and improves clinical outcomes. We assessed this association for patients with chronic viral hepatitis.

Methods

Untreated patients chronically infected with HBV (n = 500) or HCV (n = 500) were enrolled at 19 centers across India. A survey, adapted from the US CDC National Health and Nutrition Examination Survey (NHANES) questionnaire, was administered at a single visit to assess HBV/HCV knowledge, community disease awareness, treatment quality, and healthcare barriers. We developed the India Hepatitis Knowledge Index (IHKI), where a higher IHKI score (range 0-10) indicates increased hepatitis knowledge. Multivariate regression models evaluated demographic and disease factors.

Results

The overall mean IHKI score was 5.6 out of 10, with higher scores among patients with HBV (5.9) than HCV (5.3); p < 0.001. In HBV patients lower IHKI was associated with shorter disease duration, government clinic attendance (p < 0.0001), fewer personal experiences with HBV (p < 0.0001), and residing in northern India. Among HCV patients, lower IHKI was associated with shorter disease duration, community (p < 0.0001) and government clinic attendance (p < 0.0001), and fewer personal experiences with HCV (p < 0.0001). Among HBV patients, IHKI was independently associated with disease severity as assessed by MELD score, albumin, and APRI. This association was strongest for HBV patients with elevated ALT and HBV DNA >2000 IU/ml. Among HCV patients, IHKI results had no significant associations with disease severity.

Conclusions

The association of IHKI with disease underscores the need to understand connections between hepatitis knowledge and progression and may guide efforts to address patient education and awareness of chronic viral hepatitis in India.

SUBMITTER: Tamayo A

PROVIDER: S-EPMC5083769 | biostudies-literature | 2016 Nov

REPOSITORIES: biostudies-literature

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Correlates of disease-specific knowledge among patients with chronic hepatitis B or hepatitis C infection in India.

Tamayo Aracely A Shah Samir R SR Bhatia Shobna S Chowdhury Abhijit A Rao Padaki N PN Dinh Phillip P Knox Steven J SJ Gaggar Anuj A Subramanian G Mani GM Mohan Viswanathan G VG Sood Ajit A Mehta Rajiv R Sarin Shiv K SK

Hepatology international 20160504 6

<h4>Background</h4>Patient knowledge about chronic diseases increases health-promoting behaviors and improves clinical outcomes. We assessed this association for patients with chronic viral hepatitis.<h4>Methods</h4>Untreated patients chronically infected with HBV (n = 500) or HCV (n = 500) were enrolled at 19 centers across India. A survey, adapted from the US CDC National Health and Nutrition Examination Survey (NHANES) questionnaire, was administered at a single visit to assess HBV/HCV knowle ...[more]

PMID: 27146692

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Dataset Information

Correlates of disease-specific knowledge among patients with chronic hepatitis B or hepatitis C infection in India.

Background

Methods

Results

Conclusions

Publications

Correlates of disease-specific knowledge among patients with chronic hepatitis B or hepatitis C infection in India.

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