Ontology highlight
ABSTRACT:
SUBMITTER: Liu P
PROVIDER: S-EPMC5085220 | biostudies-literature | 2016 Jun
REPOSITORIES: biostudies-literature
Liu Peng P Ye Feng F Xie Xinhua X Li Xing X Tang Hailin H Li Shuaijie S Huang Xiaojia X Song Cailu C Wei Weidong W Xie Xiaoming X
Oncotarget 20160601 23
mir-101-3p has been reported to be a tumor suppressor and a promising therapeutic target in cancer. Recently, AMPK dysfunction has been highlighted in cancers, including breast cancer. The aim of this study is to investigate the biological roles of mir-101-3p and AMPK in breast cancer. Our research demonstrated that AMPK was up-regulated in breast cancer tissues and cell lines, especially in triple negative breast cancer (TNBC). High-expression of AMPK correlated with poor outcome in both total ...[more]