Ontology highlight
ABSTRACT:
SUBMITTER: Valentini M
PROVIDER: S-EPMC5085249 | biostudies-literature | 2016 Oct
REPOSITORIES: biostudies-literature
Valentini Martina M Laventie Benoît-Joseph BJ Moscoso Joana J Jenal Urs U Filloux Alain A
PLoS genetics 20161028 10
The molecular basis of second messenger signaling relies on an array of proteins that synthesize, degrade or bind the molecule to produce coherent functional outputs. Cyclic di-GMP (c-di-GMP) has emerged as a eubacterial nucleotide second messenger regulating a plethora of key behaviors, like the transition from planktonic cells to biofilm communities. The striking multiplicity of c-di-GMP control modules and regulated cellular functions raised the question of signaling specificity. Are c-di-GMP ...[more]