Ontology highlight
ABSTRACT:
SUBMITTER: Lorenzi I
PROVIDER: S-EPMC5086520 | biostudies-literature | 2016 Nov
REPOSITORIES: biostudies-literature
Lorenzi Isotta I Oeljeklaus Silke S Ronsör Christin C Bareth Bettina B Warscheid Bettina B Rehling Peter P Dennerlein Sven S
Molecular and cellular biology 20161028 22
The three conserved core subunits of the cytochrome <i>c</i> oxidase are encoded by mitochondria in close to all eukaryotes. The Cox2 subunit spans the inner membrane twice, exposing the N and C termini to the intermembrane space. For this, the N terminus is exported cotranslationally by Oxa1 and subsequently undergoes proteolytic maturation in <i>Saccharomyces cerevisiae</i> Little is known about the translocation of the C terminus, but Cox18 has been identified to be a critical protein in this ...[more]