Ubiquitin in Influenza Virus Entry and Innate Immunity.
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ABSTRACT:
SUBMITTER: Rudnicka A
PROVIDER: S-EPMC5086625 | biostudies-literature | 2016 Oct
REPOSITORIES: biostudies-literature
Publications
Ubiquitin in Influenza Virus Entry and Innate Immunity.
Rudnicka Alina A Yamauchi Yohei Y
Viruses 20161024 10
Viruses are obligatory cellular parasites. Their mission is to enter a host cell, to transfer the viral genome, and to replicate progeny whilst diverting cellular immunity. The role of ubiquitin is to regulate fundamental cellular processes such as endocytosis, protein degradation, and immune signaling. Many viruses including influenza A virus (IAV) usurp ubiquitination and ubiquitin-like modifications to establish infection. In this focused review, we discuss how ubiquitin and unanchored ubiqui ...[more]
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