Ontology highlight
ABSTRACT:
SUBMITTER: Ostadkarampour M
PROVIDER: S-EPMC5087844 | biostudies-literature | 2016
REPOSITORIES: biostudies-literature
Ostadkarampour Mahyar M Müller Malin M Öckinger Johan J Kullberg Susanna S Lindén Anders A Eklund Anders A Grunewald Johan J Wahlström Jan J
PloS one 20161031 10
Smoking influences the immune system in different ways and, hypothetically, effects on pulmonary effector and regulatory T cells emerge as potentially detrimental. Therefore, we characterized the frequencies and characteristics of CD4+ and CD8+ T cell subsets in the blood and lungs of young tobacco smokers. Bronchoalveolar lavage (BAL) and peripheral blood were obtained from healthy moderate smokers (n = 18; 2-24 pack-years) and never-smokers (n = 15), all with normal lung function. Cells were s ...[more]