Vibrio vulnificus Type 6 Secretion System 1 Contains Anti-Bacterial Properties.

ABSTRACT: Vibrio vulnificus is a bacterium responsible for severe gastroenteritis, sepsis and wound infections. Gastroenteritis and sepsis are commonly associated with the consumption of raw oysters, whereas wound infection is often associated with the handling of contaminated fish. Although classical virulence factors of this emerging pathogen are well characterised, there remains a paucity of knowledge regarding the general biology of this species. To investigate the presence of previously unreported virulence factors, we applied whole genome sequencing to a panel of ten V. vulnificus strains with varying virulence potentials. This identified two novel type 6 secretion systems (T6SSs), systems that are known to have a role in bacterial virulence and population dynamics. By utilising a range of mol

SUBMITTER: Church SR 

PROVIDER: S-EPMC5087951 | biostudies-literature | 2016

REPOSITORIES: biostudies-literature