Serum bilirubin levels are positively associated with glycemic variability in women with type 2 diabetes.

ABSTRACT:

Aims/introduction

Glycemic variability is known to induce oxidative stress. We investigated the relationships between glycemic variability and serum bilirubin levels, an endogenous anti-oxidant, in patients with diabetes.

Materials and methods

A cross-sectional study was carried out with 77 patients with type 2 diabetes who had been recruited to two clinical studies from 2008 to 2014. There were no participants with diseases of the pancreas, liver, biliary tract and chronic renal insufficiency. Glycemic variation was calculated by a continuous glucose monitoring system, and correlation analyses were carried out to evaluate their association with bilirubin levels. Multiple linear regression was carried out to identify independent factors influencing bilirubin levels and glyce

SUBMITTER: Kim LK 

PROVIDER: S-EPMC5089950 | biostudies-literature | 2016 Nov

REPOSITORIES: biostudies-literature