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Evidence for Human Adaptation and Foodborne Transmission of Livestock-Associated Methicillin-Resistant Staphylococcus aureus.


ABSTRACT: We investigated the evolution and epidemiology of a novel livestock-associated methicillin-resistant Staphylococcus aureus strain, which colonizes and infects urban-dwelling Danes even without a Danish animal reservoir. Genetic evidence suggests both poultry and human adaptation, with poultry meat implicated as a probable source.

SUBMITTER: Larsen J 

PROVIDER: S-EPMC5091345 | biostudies-literature | 2016 Nov

REPOSITORIES: biostudies-literature

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Evidence for Human Adaptation and Foodborne Transmission of Livestock-Associated Methicillin-Resistant Staphylococcus aureus.

Larsen Jesper J   Stegger Marc M   Andersen Paal S PS   Petersen Andreas A   Larsen Anders R AR   Westh Henrik H   Agersø Yvonne Y   Fetsch Alexandra A   Kraushaar Britta B   Käsbohrer Annemarie A   Feβler Andrea T AT   Schwarz Stefan S   Cuny Christiane C   Witte Wolfgang W   Butaye Patrick P   Denis Olivier O   Haenni Marisa M   Madec Jean-Yves JY   Jouy Eric E   Laurent Frederic F   Battisti Antonio A   Franco Alessia A   Alba Patricia P   Mammina Caterina C   Pantosti Annalisa A   Monaco Monica M   Wagenaar Jaap A JA   de Boer Enne E   van Duijkeren Engeline E   Heck Max M   Domínguez Lucas L   Torres Carmen C   Zarazaga Myriam M   Price Lance B LB   Skov Robert L RL  

Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20160920 10


We investigated the evolution and epidemiology of a novel livestock-associated methicillin-resistant Staphylococcus aureus strain, which colonizes and infects urban-dwelling Danes even without a Danish animal reservoir. Genetic evidence suggests both poultry and human adaptation, with poultry meat implicated as a probable source. ...[more]

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