Ontology highlight
ABSTRACT:
SUBMITTER: Ahmed I
PROVIDER: S-EPMC5095006 | biostudies-literature | 2016 Jun
REPOSITORIES: biostudies-literature
Ahmed Ikhlak I Karedath Thasni T Andrews Simeon S SS Al-Azwani Iman K IK Mohamoud Yasmin Ali YA Querleu Denis D Rafii Arash A Malek Joel A JA
Oncotarget 20160601 24
Recently, a class of endogenous species of RNA called circular RNA (circRNA) has been shown to regulate gene expression in mammals and their role in cellular function is just beginning to be understood. To investigate the role of circRNAs in ovarian cancer, we performed paired-end RNA sequencing of primary sites, peritoneal and lymph node metastases from three patients with stage IIIC ovarian cancer. We developed an in-house computational pipeline to identify and characterize the circRNA express ...[more]