Dataset Information

Understanding the Antifungal Mechanism of Ag@ZnO Core-shell Nanocomposites against Candida krusei.

ABSTRACT: In the present paper, facile synthesis of Ag@ZnO core-shell nanocomposites is reported where zinc oxide is coated on biogenic silver nanoparticles synthesized using Andrographis paniculata and Aloe vera leaf extract. Structural features of as synthesized nanocomposites are characterized by UV-visible spectroscopy, XRD, and FTIR. Morphology of the above core-shell nanocomposites is investigated by electron microscopy. As synthesized nanocomposite material has shown antimicrobial activity against Candida krusei, which is an opportunistic pathogen known to cause candidemia. The possible mode of activity of the above material has been studied by in-vitro molecular techniques. Our investigations have shown that surface coating of biogenic silver nanoparticles by zinc oxide has increased its antimicrobial efficiency against Candida krusei, while decreasing its toxicity towards A431 human epidermoid carcinoma cell lines.

SUBMITTER: Das B

PROVIDER: S-EPMC5095647 | biostudies-literature | 2016 Nov

REPOSITORIES: biostudies-literature

ACCESS DATA

Publications

Understanding the Antifungal Mechanism of Ag@ZnO Core-shell Nanocomposites against Candida krusei.

Das Bhaskar B Khan Md Imran MI Jayabalan R R Behera Susanta K SK Yun Soon-Il SI Tripathy Suraj K SK Mishra Amrita A

Scientific reports 20161104

In the present paper, facile synthesis of Ag@ZnO core-shell nanocomposites is reported where zinc oxide is coated on biogenic silver nanoparticles synthesized using Andrographis paniculata and Aloe vera leaf extract. Structural features of as synthesized nanocomposites are characterized by UV-visible spectroscopy, XRD, and FTIR. Morphology of the above core-shell nanocomposites is investigated by electron microscopy. As synthesized nanocomposite material has shown antimicrobial activity against ...[more]

PMID: 27812015

Similar Datasets

Project description:Breeding programs rely on light wavelength, intensity, and photoperiod for rapid success. In this study, we investigated the ability of Ag/ZnO nanoparticles (NPs) to improve the photosynthesis and growth of wheat under simulated full solar spectrum conditions. The world population is increasing rapidly, it is necessary to increase the number of crops in order to ensure the world's food security. Conventional breeding is time-consuming and expensive, so new techniques such as rapid breeding are needed. Rapid breeding shows promise in increasing crop yields by controlling photoperiod and environmental factors in growth regulators. However, achieving optimum growth and photosynthesis rates is still a challenge. Here, we used various methods to evaluate the effects of Ag/ZnO NPs on rice seeds. Using bioinformatics simulations, we evaluated the light-harvesting efficiency of chlorophyll a in the presence of Ag/ZnO NPs. Chemically synthesized Ag/ZnO nanoparticles were applied to rice grains at different concentrations (0-50 mg/L) and subjected to a 12-h preparation time. Evaluation of seed germination rate and growth response in different light conditions using a Light Emitting Diode (LED) growth chamber that simulates a rapid growth system. The analysis showed that the surface plasmon resonance of Ag/ZnO NPs increased 38-fold, resulting in a 160-fold increase in the light absorption capacity of chlorophyll. These estimates are supported by experimental results showing an 18% increase in the yield of rice seeds treated with 15 mg/L Ag/ZnO NPs. More importantly, the treated crops showed a 2.5-fold increase in growth and a 1.4-fold increase in chlorophyll content under the simulated full sun spectrum (4500 lx) and a 16-h light/8-h dark photoperiod. More importantly, these effects are achieved without oxidative or lipid peroxidative damage. Our findings offer a good idea to increase crop growth by improving photosynthesis using Ag/ZnO nanoparticle mixture. To develop this approach, future research should go towards optimizing nanoparticles, investigating the long-term effects, and exploring the applicability of this process in many products. The inclusion of Ag/ZnO NPs in rapid breeding programs has the potential to transform crops by reducing production and increasing agricultural productivity.

Dataset Information

Understanding the Antifungal Mechanism of Ag@ZnO Core-shell Nanocomposites against Candida krusei.

Publications

Understanding the Antifungal Mechanism of Ag@ZnO Core-shell Nanocomposites against Candida krusei.

Similar Datasets

OmicsDI is part of the ELIXIR infrastructure

Tweets