Ontology highlight
ABSTRACT:
SUBMITTER: King AJ
PROVIDER: S-EPMC5095812 | biostudies-literature | 2016 Sep
REPOSITORIES: biostudies-literature
Chembiochem : a European journal of chemical biology 20160715 17
The Euphorbiaceae produce a wide variety of bioactive diterpenoids. These include the lathyranes, which have received much interest due to their ability to inhibit the ABC transporters responsible for the loss of efficacy of many chemotherapy drugs. The lathyranes are also intermediates in the biosynthesis of range of other bioactive diterpenoids with potential applications in the treatment of pain, HIV and cancer. We report here a gene cluster from Jatropha curcas that contains the genes requir ...[more]