Ontology highlight
ABSTRACT:
SUBMITTER: Hunter MS
PROVIDER: S-EPMC5097167 | biostudies-literature | 2016 Nov
REPOSITORIES: biostudies-literature
Hunter Mark S MS Yoon Chun Hong CH DeMirci Hasan H Sierra Raymond G RG Dao E Han EH Ahmadi Radman R Aksit Fulya F Aquila Andrew L AL Ciftci Halilibrahim H Guillet Serge S Hayes Matt J MJ Lane Thomas J TJ Liang Meng M Lundström Ulf U Koglin Jason E JE Mgbam Paul P Rao Yashas Y Zhang Lindsey L Wakatsuki Soichi S Holton James M JM Boutet Sébastien S
Nature communications 20161104
Structural information about biological macromolecules near the atomic scale provides important insight into the functions of these molecules. To date, X-ray crystallography has been the predominant method used for macromolecular structure determination. However, challenges exist when solving structures with X-rays, including the phase problem and radiation damage. X-ray-free electron lasers (X-ray FELs) have enabled collection of diffraction information before the onset of radiation damage, yet ...[more]