Ontology highlight
ABSTRACT:
SUBMITTER: Imagawa Y
PROVIDER: S-EPMC5097171 | biostudies-literature | 2016 Nov
REPOSITORIES: biostudies-literature
Imagawa Yusuke Y Saitoh Tatsuya T Tsujimoto Yoshihide Y
Nature communications 20161104
Programmed cell death has a crucial role in various biological events, including developmental morphogenesis. Recent evidence indicates that necrosis contributes to programmed cell death in addition to apoptosis, but it is unclear whether necrosis acts as a compensatory mechanism for failure of apoptosis or has an intrinsic role during development. In contrast to apoptosis, there have been no techniques for imaging physiological necrosis in vivo. Here we employ vital staining using propidium iod ...[more]