Ontology highlight
ABSTRACT:
SUBMITTER: Mitterer V
PROVIDER: S-EPMC5098186 | biostudies-literature | 2016 Nov
REPOSITORIES: biostudies-literature
Mitterer Valentin V Gantenbein Nadine N Birner-Gruenberger Ruth R Murat Guillaume G Bergler Helmut H Kressler Dieter D Pertschy Brigitte B
Scientific reports 20161107
After their cytoplasmic synthesis, ribosomal proteins need to be transported into the nucleus, where they assemble with ribosomal RNA into pre-ribosomal particles. Due to their physicochemical properties, they need protection from aggregation on this path. Newly synthesized ribosomal protein Rps3 forms a dimer that is associated with one molecule of its specific chaperone Yar1. Here we report that redundant pathways contribute to the nuclear import of Rps3, with the classical importin α/β pathwa ...[more]