Concurrent profiling of polar metabolites and lipids in human plasma using HILIC-FTMS.
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ABSTRACT:
SUBMITTER: Cai X
PROVIDER: S-EPMC5098236 | biostudies-literature | 2016 Nov
REPOSITORIES: biostudies-literature
Publications
Concurrent profiling of polar metabolites and lipids in human plasma using HILIC-FTMS.
Scientific reports 20161107
Blood plasma is the most popularly used sample matrix for metabolite profiling studies, which aim to achieve global metabolite profiling and biomarker discovery. However, most of the current studies on plasma metabolite profiling focused on either the polar metabolites or lipids. In this study, a comprehensive analysis approach based on HILIC-FTMS was developed to concurrently examine polar metabolites and lipids. The HILIC-FTMS method was developed using mixed standards of polar metabolites and ...[more]
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