Ontology highlight
ABSTRACT:
SUBMITTER: Wang X
PROVIDER: S-EPMC5099878 | biostudies-literature | 2016 Nov
REPOSITORIES: biostudies-literature
Wang Xingxing X Li Yuan Y Dai Yi Y Liu Qinqiang Q Ning Shilong S Liu Jiao J Shen Zhaoxia Z Zhu Dongmei D Jiang Fei F Zhang Jianping J Li Zhong Z
Scientific reports 20161108
Gastric carcinoma (GC) is the second leading cause of cancer-related mortality worldwide. The efficacy of standard chemotherapy for GC, such as cisplatin (CDDP), is dissatisfactory partly due to the toxic/side-effects. Sulforaphane (SFN), which exhibits effective anti-cancer functions, is a phytochemical converted from cruciferous plants. Our present study aimed to identify whether SFN could enhance the anti-cancer effects of low-dose CDDP and to determine the underlying mechanisms. Herein, co-e ...[more]