Evolution of Protein Domain Repeats in Metazoa.
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ABSTRACT:
SUBMITTER: Schuler A
PROVIDER: S-EPMC5100051 | biostudies-literature | 2016 Dec
REPOSITORIES: biostudies-literature
Publications
Evolution of Protein Domain Repeats in Metazoa.
Schüler Andreas A Bornberg-Bauer Erich E
Molecular biology and evolution 20160926 12
Repeats are ubiquitous elements of proteins and they play important roles for cellular function and during evolution. Repeats are, however, also notoriously difficult to capture computationally and large scale studies so far had difficulties in linking genetic causes, structural properties and evolutionary trajectories of protein repeats. Here we apply recently developed methods for repeat detection and analysis to a large dataset comprising over hundred metazoan genomes. We find that repeats in ...[more]
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