Ontology highlight
ABSTRACT:
SUBMITTER: Nagesh PKB
PROVIDER: S-EPMC5100699 | biostudies-literature | 2016 Aug
REPOSITORIES: biostudies-literature
Nagesh Prashanth K B PKB Johnson Nia R NR Boya Vijaya K N VKN Chowdhury Pallabita P Othman Shadi F SF Khalilzad-Sharghi Vahid V Hafeez Bilal B BB Ganju Aditya A Khan Sheema S Behrman Stephen W SW Zafar Nadeem N Chauhan Subhash C SC Jaggi Meena M Yallapu Murali M MM
Colloids and surfaces. B, Biointerfaces 20160326
Docetaxel (Dtxl) is currently the most common therapeutic option for prostate cancer (PC). However, adverse side effects and problems associated with chemo-resistance limit its therapeutic outcome in clinical settings. A targeted nanoparticle system to improve its delivery to and activity at the tumor site could be an attractive strategy for PC therapy. Therefore, the objective of this study was to develop and determine the anti-cancer efficacy of a novel docetaxel loaded, prostate specific memb ...[more]