Ontology highlight
ABSTRACT:
SUBMITTER: Sorret LL
PROVIDER: S-EPMC5103004 | biostudies-literature | 2016 Nov
REPOSITORIES: biostudies-literature
Sorret Lea L LL DeWinter Madison A MA Schwartz Daniel K DK Randolph Theodore W TW
Biophysical journal 20161101 9
Dynamic light scattering can be used to measure the diffusivity of a protein within a formulation. The dependence of molecular diffusivity on protein concentration (traditionally expressed in terms of the interaction parameter k<sub>D</sub>) is often used to infer whether protein-protein interactions are repulsive or attractive, resulting in solutions that are colloidally stable or unstable, respectively. However, a number of factors unrelated to intermolecular forces can also impact protein dif ...[more]