Ontology highlight
ABSTRACT:
SUBMITTER: De Ameida Melo M
PROVIDER: S-EPMC5103674 | biostudies-literature | 2016 Nov
REPOSITORIES: biostudies-literature
De Ameida Melo Mariella M De Vasconcelos-Valença Rodrigo José RJ Neto Fidelis Manes FM Borges Rafael Soares RS Costa-Silva Danylo Rafhael DR Da Conceição Barros-Oliveira Maria M Borges Umbelina Soares US Alencar Airlane Pereira AP Silva Vladimir Costa VC Da Silva Benedito Borges BB
Biomedical reports 20161004 5
At present, there is controversy regarding the efficacy of tamoxifen in breast cancer patients who are carriers of cytochrome P450 2D6 (CYP2D6) gene polymorphisms, in terms of recurrence and overall survival. Thus, the aim of the present study was to investigate the association of the CYP2D6 *4, *10 and *17 gene polymorphisms with breast cancer recurrence in a Brazilian population. The cohort comprised 40 receptor-positive breast cancer patients without recurrence and 40 with distant recurrence. ...[more]