Genetics and epigenetics of melanoma.
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ABSTRACT:
SUBMITTER: Zhang XY
PROVIDER: S-EPMC5103895 | biostudies-literature | 2016 Nov
REPOSITORIES: biostudies-literature
Publications
Genetics and epigenetics of melanoma.
Zhang Xiao-Ying XY Zhang Pei-Ying PY
Oncology letters 20160905 5
Cancer affects multiple organs in the body Malignant melanoma involves the invasion of skin and occasionally mucosal membrane or eye choroidal tissues. The incidence of cutaneous malignant melanoma is on the increase worldwide and is a major concern in current research. The increase is associated with UV irradiation-induced genetic aberrations that stimulate skin melanocytes to develop unlimited growth. This eventually leads to cell immortality, which in turn causes metastases. The present revie ...[more]
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