Ontology highlight
ABSTRACT:
SUBMITTER: Yan XH
PROVIDER: S-EPMC5105127 | biostudies-literature | 2016 Nov
REPOSITORIES: biostudies-literature
Yan Xiao-Hui XH Yi Ping P Cao Pei P Yang Shi-Ying SY Fang Xin X Zhang Yu Y Bin Wu Leng Ying Y Di Ying-Tong YT Lv Yang Y Hao Xiao-Jiang XJ
Scientific reports 20161111
Two new 16-nor limonoids, harperspinoids A and B (1 and 2), with a unique 7/5/5/6/5 ring system, have been isolated from the plant Harrisonia perforate together with a known one, Harperforin G (3). Their structures were elucidated by NMR spectroscopy, X-ray diffraction analysis and computational modelling. Compound 1 exists as polymorphic crystals. Conformations of 1 in solution were further discussed based on the computational results. These compounds exhibited notable inhibitory activity again ...[more]