Ontology highlight
ABSTRACT:
SUBMITTER: Hu J
PROVIDER: S-EPMC5105168 | biostudies-literature | 2016 Nov
REPOSITORIES: biostudies-literature
Hu Jing J Khodadadi-Jamayran Alireza A Mao Miaowei M Shah Kushani K Yang Zhenhua Z Nasim Md Talat MT Wang Zefeng Z Jiang Hao H
Nature communications 20161108
Alternative splicing of pre-mRNAs significantly contributes to the complexity of gene expression in higher organisms, but the regulation of the splice site selection remains incompletely understood. We have previously demonstrated that a chromatin-associated protein, AKAP95, has a remarkable activity in enhancing chromatin transcription. In this study, we show that AKAP95 interacts with many factors involved in transcription and RNA processing, including selective groups of hnRNP proteins, throu ...[more]