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Surgical management of breast cancer in China: A 15-year single-center retrospective study of 18,502 patients.


ABSTRACT: The aim of the study was to review the surgical trends in breast cancer treatment in China over the past 15 years and to explore the possible factors related to the choice of surgical modality.The medical records of 18,502 patients with unilateral early stage breast cancer who underwent surgery from January 1999 to December 2013 at our institute were retrospectively reviewed. The utilization of different surgical modalities and the associated clinicopathological factors were analyzed. Furthermore, the prognostic role of surgical modality was also evaluated.The median patient age was 50.0 years. According to the pTNM staging system, 12.5% of the patients were classified as stage 0; 30.2% as stage I; 40.0% as stage II; and 17.3% as stage III. In total, 9.3% of the patients could not be staged. Overall, 67.1% of the breast cancer cases were estrogen receptor (ER) positive. The pattern of breast cancer surgery has changed tremendously over the past 15 years (P?

SUBMITTER: Huang NS 

PROVIDER: S-EPMC5106045 | biostudies-literature | 2016 Nov

REPOSITORIES: biostudies-literature

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Surgical management of breast cancer in China: A 15-year single-center retrospective study of 18,502 patients.

Huang Nai-Si NS   Liu Meng-Ying MY   Chen Jia-Jian JJ   Yang Ben-Long BL   Xue Jing-Yan JY   Quan Chen-Lian CL   Mo Miao M   Liu Guang-Yu GY   Shen Zhen-Zhou ZZ   Shao Zhi-Min ZM   Wu Jiong J  

Medicine 20161101 45


The aim of the study was to review the surgical trends in breast cancer treatment in China over the past 15 years and to explore the possible factors related to the choice of surgical modality.The medical records of 18,502 patients with unilateral early stage breast cancer who underwent surgery from January 1999 to December 2013 at our institute were retrospectively reviewed. The utilization of different surgical modalities and the associated clinicopathological factors were analyzed. Furthermor  ...[more]

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