Ontology highlight
ABSTRACT:
SUBMITTER: Van Tyne D
PROVIDER: S-EPMC5106311 | biostudies-literature | 2016 Nov
REPOSITORIES: biostudies-literature
Van Tyne Daria D Ciolino Joseph B JB Wang Jay J Durand Marlene L ML Gilmore Michael S MS
JAMA ophthalmology 20161101 11
<h4>Importance</h4>Extended-spectrum β-lactamase (ESBL)-producing Escherichia coli are highly antibiotic resistant, and primary ocular infection by ESBL E coli has rarely been reported. A novel mutation conferring phagocytosis resistance would position a strain well to infect the cornea.<h4>Observations</h4>A woman with recurrent keratitis presented with a corneal ulcer, which was culture positive for ESBL E coli. Resistant to nearly all other antimicrobials, the infection was treated with amika ...[more]