Ontology highlight
ABSTRACT:
SUBMITTER: Taha AY
PROVIDER: S-EPMC5106341 | biostudies-literature | 2018 Nov
REPOSITORIES: biostudies-literature
Taha Ameer Y AY Hennebelle Marie M Yang Jun J Zamora Daisy D Rapoport Stanley I SI Hammock Bruce D BD Ramsden Christopher E CE
Prostaglandins, leukotrienes, and essential fatty acids 20160511
Linoleic acid (LA, 18:2n-6) is the most abundant polyunsaturated fatty acid in the North American diet and is a precursor to circulating bioactive fatty acid metabolites implicated in brain disorders. This exploratory study tested the effects of increasing dietary LA on plasma and cerebral cortex metabolites derived from LA, its elongation-desaturation products dihomo-gamma linolenic (DGLA, 20:3n-6) acid and arachidonic acid (AA, 20:4n-6), as well as omega-3 alpha-linolenic (α-LNA, 18:3n-3), eic ...[more]