Internal states drive nutrient homeostasis by modulating exploration-exploitation trade-off.

ABSTRACT: Internal states can profoundly alter the behavior of animals. A quantitative understanding of the behavioral changes upon metabolic challenges is key to a mechanistic dissection of how animals maintain nutritional homeostasis. We used an automated video tracking setup to characterize how amino acid and reproductive states interact to shape exploitation and exploration decisions taken by adult Drosophila melanogaster. We find that these two states have specific effects on the decisions to stop at and leave proteinaceous food patches. Furthermore, the internal nutrient state defines the exploration-exploitation trade-off: nutrient-deprived flies focus on specific patches while satiated flies explore more globally. Finally, we show that olfaction mediates the efficient recognition of y

SUBMITTER: Corrales-Carvajal VM 

PROVIDER: S-EPMC5108593 | biostudies-literature | 2016 Oct

REPOSITORIES: biostudies-literature