Ontology highlight
ABSTRACT:
SUBMITTER: Ito Y
PROVIDER: S-EPMC5109538 | biostudies-literature | 2016 Nov
REPOSITORIES: biostudies-literature
Ito Yoichiro Y Kitagawa Takao T Yamanishi Mamoru M Katahira Satoshi S Izawa Shingo S Irie Kenji K Furutani-Seiki Makoto M Matsuyama Takashi T
Scientific reports 20161115
Post-transcriptional upregulation is an effective way to increase the expression of transgenes and thus maximize the yields of target chemicals from metabolically engineered organisms. Refractory elements in the 3' untranslated region (UTR) that increase mRNA half-life might be available. In Saccharomyces cerevisiae, several terminator regions have shown activity in increasing the production of proteins by upstream coding genes; among these terminators the DIT1 terminator has the highest activit ...[more]