Ontology highlight
ABSTRACT:
SUBMITTER: Li J
PROVIDER: S-EPMC5109731 | biostudies-literature | 2016 Nov
REPOSITORIES: biostudies-literature
Virology journal 20161114 1
<h4>Background</h4>This study aimed at reseaching the immune effect of porcine circovirus type 2 (PCV2) DNA vaccine containing CpG motif on mice.<h4>Methods</h4>A total of 40 6-week-old female BALB/c mice were randomly divided into four groups which were immunized by 18CpG-pVAX1-ORF2, pVAX1-ORF2, pVAX1 and PBS, respectively, and immunized again 2 weeks later. All mice were challenged with 0.2 mL PCV2 cells virulent strain SD (10<sup>6.0</sup> TCID<sub>50</sub>/mL) after 4 weeks. Average daily ga ...[more]