Ontology highlight
ABSTRACT:
SUBMITTER: Rini BI
PROVIDER: S-EPMC5109802 | biostudies-literature | 2016
REPOSITORIES: biostudies-literature
Rini Brian I BI McDermott David F DF Hammers Hans H Bro William W Bukowski Ronald M RM Faba Bernard B Faba Jo J Figlin Robert A RA Hutson Thomas T Jonasch Eric E Joseph Richard W RW Leibovich Bradley C BC Olencki Thomas T Pantuck Allan J AJ Quinn David I DI Seery Virginia V Voss Martin H MH Wood Christopher G CG Wood Laura S LS Atkins Michael B MB
Journal for immunotherapy of cancer 20161115
Immunotherapy has produced durable clinical benefit in patients with metastatic renal cell cancer (RCC). In the past, patients treated with interferon-alpha (IFN) and interleukin-2 (IL-2) have achieved complete responses, many of which have lasted for multiple decades. More recently, a large number of new agents have been approved for RCC, several of which attack tumor angiogenesis by inhibiting vascular endothelial growth factors (VEGF) and VEGF receptors (VEGFR), as well as tumor metabolism, i ...[more]