Ontology highlight
ABSTRACT:
SUBMITTER: Morita M
PROVIDER: S-EPMC5109995 | biostudies-literature | 2016 Oct
REPOSITORIES: biostudies-literature
Morita Makiko M Wang Yanyan Y Sasaoka Toshikuni T Okada Kinya K Niwa Minae M Sawa Akira A Hikida Takatoshi T
Molecular neuropsychiatry 20160721 3
The corticostriatothalamic circuit regulates learning behaviors via dopamine neurotransmission. D2 long (D2L) receptors are an isoform of dopamine D2 receptors (D2Rs) and may act mainly at postsynaptic sites. It is well known that D2Rs influence high brain functions, but the roles of individual D2R isoforms are still unclear. To assess the influence of D2L receptors in visual discrimination learning, we performed visual discrimination and reversal tasks with D2L knockout mice using a touchscreen ...[more]