Genome-Wide Transcriptional Regulation and Chromosome Structural Arrangement by GalR in E. coli.
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ABSTRACT:
SUBMITTER: Qian Z
PROVIDER: S-EPMC5110547 | biostudies-literature | 2016
REPOSITORIES: biostudies-literature
Publications
Genome-Wide Transcriptional Regulation and Chromosome Structural Arrangement by GalR in <i>E. coli</i>.
Qian Zhong Z Trostel Andrei A Lewis Dale E A DE Lee Sang Jun SJ He Ximiao X Stringer Anne M AM Wade Joseph T JT Schneider Thomas D TD Durfee Tim T Adhya Sankar S
Frontiers in molecular biosciences 20161116
The regulatory protein, GalR, is known for controlling transcription of genes related to D-galactose metabolism in <i>Escherichia coli</i>. Here, using a combination of experimental and bioinformatic approaches, we identify novel GalR binding sites upstream of several genes whose function is not directly related to D-galactose metabolism. Moreover, we do not observe regulation of these genes by GalR under standard growth conditions. Thus, our data indicate a broader regulatory role for GalR, and ...[more]
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