Ontology highlight
ABSTRACT:
SUBMITTER: Woroniecki RP
PROVIDER: S-EPMC5110572 | biostudies-literature | 2016
REPOSITORIES: biostudies-literature
Woroniecki Robert P RP Ng Derek K DK Limou Sophie S Winkler Cheryl A CA Reidy Kimberly J KJ Mitsnefes Mark M Sampson Matthew G MG Wong Craig S CS Warady Bradley A BA Furth Susan L SL Kopp Jeffrey B JB Kaskel Frederick J FJ
Frontiers in pediatrics 20161117
<h4>Background and objectives</h4>African-American (AA) children with focal segmental glomerulosclerosis (FSGS) have later onset disease that progresses more rapidly than in non-AA children. It is unclear how <i>APOL1</i> genotypes contribute to kidney disease risk, progression, and cardiovascular morbidity in children.<h4>Design setting participants and measurements</h4>We examined the prevalence of <i>APOL1</i> genotypes and associated cardiovascular phenotypes among children with FSGS in the ...[more]