Ontology highlight
ABSTRACT:
SUBMITTER: Sholl LM
PROVIDER: S-EPMC5111542 | biostudies-literature | 2016 Nov
REPOSITORIES: biostudies-literature
Sholl Lynette M LM Do Khanh K Shivdasani Priyanka P Cerami Ethan E Dubuc Adrian M AM Kuo Frank C FC Garcia Elizabeth P EP Jia Yonghui Y Davineni Phani P Abo Ryan P RP Pugh Trevor J TJ van Hummelen Paul P Thorner Aaron R AR Ducar Matthew M Berger Alice H AH Nishino Mizuki M Janeway Katherine A KA Church Alanna A Harris Marian M Ritterhouse Lauren L LL Campbell Joshua D JD Rojas-Rudilla Vanesa V Ligon Azra H AH Ramkissoon Shakti S Cleary James M JM Matulonis Ursula U Oxnard Geoffrey R GR Chao Richard R Tassell Vanessa V Christensen James J Hahn William C WC Kantoff Philip W PW Kwiatkowski David J DJ Johnson Bruce E BE Meyerson Matthew M Garraway Levi A LA Shapiro Geoffrey I GI Rollins Barrett J BJ Lindeman Neal I NI MacConaill Laura E LE
JCI insight 20161117 19
<b>BACKGROUND.</b> Comprehensive genomic profiling of a patient's cancer can be used to diagnose, monitor, and recommend treatment. Clinical implementation of tumor profiling in an enterprise-wide, unselected cancer patient population has yet to be reported. <b>METHODS.</b> We deployed a hybrid-capture and massively parallel sequencing assay (OncoPanel) for all adult and pediatric patients at our combined cancer centers. Results were categorized by pathologists based on actionability. We report ...[more]