Ontology highlight
ABSTRACT:
SUBMITTER: Konno T
PROVIDER: S-EPMC5112913 | biostudies-literature | 2016
REPOSITORIES: biostudies-literature
Konno Tadayoshi T Nakano Rei R Mamiya Ryo R Tsuchiya Hisashi H Kitanaka Taku T Namba Shinichi S Kitanaka Nanako N Okabayashi Ken K Narita Takanori T Sugiya Hiroshi H
PloS one 20161116 11
Acute kidney injury (AKI) is characterized by a sudden loss of renal function. Early recognition of AKI, especially in critically ill patients, is essential for adequate therapy. Currently, neutrophil gelatinase-associated lipocalin (NGAL) is considered to be an effective biomarker of AKI; however, the regulation of its expression and function in renal tubular cells remains unclear. In this study, we investigated the regulation of the expression and function of NGAL in IL-1β-treated Madin-Darby ...[more]