Ontology highlight
ABSTRACT:
SUBMITTER: Junge S
PROVIDER: S-EPMC5115705 | biostudies-literature | 2016
REPOSITORIES: biostudies-literature
Junge Sibylle S Görlich Dennis D den Reijer Martijn M Wiedemann Bärbel B Tümmler Burkhard B Ellemunter Helmut H Dübbers Angelika A Küster Peter P Ballmann Manfred M Koerner-Rettberg Cordula C Große-Onnebrink Jörg J Heuer Eberhardt E Sextro Wolfgang W Mainz Jochen G JG Hammermann Jutta J Riethmüller Joachim J Graepler-Mainka Ute U Staab Doris D Wollschläger Bettina B Szczepanski Rüdiger R Schuster Antje A Tegtmeyer Friedrich-Karl FK Sutharsan Sivagurunathan S Wald Alexandra A Nofer Jerzy-Roch JR van Wamel Willem W Becker Karsten K Peters Georg G Kahl Barbara C BC
PloS one 20161118 11
<h4>Background</h4>Staphylococcus aureus is an important pathogen in cystic fibrosis (CF). However, it is not clear which factors are associated with worse lung function in patients with persistent S. aureus airway cultures. Our main hypothesis was that patients with high S. aureus density in their respiratory specimens would more likely experience worsening of their lung disease than patients with low bacterial loads.<h4>Methods</h4>Therefore, we conducted an observational prospective longitudi ...[more]