Thrombolysis in Stroke within 30 Minutes: Results of the Acute Brain Care Intervention Study.

ABSTRACT:

Background and purpose

Time is brain: benefits of intravenous thrombolysis (IVT) in ischemic stroke last for 4.5 hours but rapidly decrease as time progresses following symptom onset. The goal of the Acute Brain Care (ABC) intervention study was to reduce the door-to-needle time (DNT) to ≤30 minutes by optimizing in-hospital stroke treatment.

Methods

We performed a single-centre before (pre-intervention period: 2000-2005) versus after (post-intervention period: 2006-2012) comparison in a cohort of consecutive patients treated with IVT. The intervention consisted of the implementation of a multidisciplinary stroke protocol combining simple strategies to reduce the DNT. Primary endpoint was the DNT, presented as proportion ≤30 minutes and median time. Secondary clinical endpoi

SUBMITTER: Zinkstok SM 

PROVIDER: S-EPMC5115772 | biostudies-literature | 2016

REPOSITORIES: biostudies-literature