Impact of cervical screening on cervical cancer mortality: estimation using stage-specific results from a nested case-control study.

ABSTRACT:

Background

It is well established that screening can prevent cervical cancer, but the magnitude of the impact of regular screening on cervical cancer mortality is unknown.

Methods

Population-based case-control study using prospectively recorded cervical screening data, England 1988-2013. Case women had cervical cancer diagnosed during April 2007-March 2013 aged 25-79 years (N=11 619). Two cancer-free controls were individually age matched to each case. We used conditional logistic regression to estimate the odds ratio (OR) of developing stage-specific cancer for women regularly screened or irregularly screened compared with women not screened in the preceding 15 years. Mortality was estimated from excess deaths within 5 years of diagnosis using stage-specific 5-year relative

SUBMITTER: Landy R 

PROVIDER: S-EPMC5117785 | biostudies-literature | 2016 Oct

REPOSITORIES: biostudies-literature