Ontology highlight
ABSTRACT:
SUBMITTER: Inoue K
PROVIDER: S-EPMC5118547 | biostudies-literature | 2016 Nov
REPOSITORIES: biostudies-literature
Inoue Keiichi K Ito Shota S Kato Yoshitaka Y Nomura Yurika Y Shibata Mikihiro M Uchihashi Takayuki T Tsunoda Satoshi P SP Kandori Hideki H
Nature communications 20161117
Light-driven outward H<sup>+</sup> pumps are widely distributed in nature, converting sunlight energy into proton motive force. Here we report the characterization of an oppositely directed H<sup>+</sup> pump with a similar architecture to outward pumps. A deep-ocean marine bacterium, Parvularcula oceani, contains three rhodopsins, one of which functions as a light-driven inward H<sup>+</sup> pump when expressed in Escherichia coli and mouse neural cells. Detailed mechanistic analyses of the pur ...[more]