Ontology highlight
ABSTRACT:
SUBMITTER: Hu Y
PROVIDER: S-EPMC5119568 | biostudies-literature | 2016 Dec
REPOSITORIES: biostudies-literature
Hu Yanmei Y Bernal Alejandra A Bullard James M JM Zhang Yonghong Y
Protein science : a publication of the Protein Society 20160926 12
Pseudomonas aeruginosa is an opportunistic bacterial pathogen and a primary cause of nosocomial infection in humans. The rate of antibiotic resistance in P. aeruginosa is increasing worldwide leading to an unmet need for discovery of new chemical compounds distinctly different from present antimicrobials. Protein synthesis is an essential metabolic process and a validated target for the development of new antibiotics. Initiation factor 1 from P. aeruginosa (Pa-IF1) is the smallest of the three i ...[more]