Ontology highlight
ABSTRACT:
SUBMITTER: Bandiera S
PROVIDER: S-EPMC5120759 | biostudies-literature | 2016 Oct
REPOSITORIES: biostudies-literature
Bandiera Simonetta S Billie Bian C C Hoshida Yujin Y Baumert Thomas F TF Zeisel Mirjam B MB
Current opinion in virology 20161011
Hepatitis C virus (HCV) infection is one of the major causes of advanced liver disease and hepatocellular carcinoma (HCC) worldwide. While the knowledge about the molecular virology of HCV infection has markedly advanced, the molecular mechanisms of disease progression leading to fibrosis, cirrhosis and HCC are still unclear. Accumulating experimental and clinical studies indicate that HCV may drive hepatocarcinogenesis directly via its proteins or transcripts, and/or indirectly through inductio ...[more]