Ontology highlight
ABSTRACT:
SUBMITTER: Swales JG
PROVIDER: S-EPMC5121636 | biostudies-literature | 2016 Nov
REPOSITORIES: biostudies-literature
Swales John G JG Strittmatter Nicole N Tucker James W JW Clench Malcolm R MR Webborn Peter J H PJH Goodwin Richard J A RJA
Scientific reports 20161124
Liquid extraction surface analysis mass spectrometry imaging (LESA-MSI) has been shown to be an effective tissue profiling and imaging technique, producing robust and reliable qualitative distribution images of an analyte or analytes in tissue sections. Here, we expand the use of LESA-MSI beyond qualitative analysis to a quantitative analytical technique by employing a mimetic tissue model previously shown to be applicable for MALDI-MSI quantitation. Liver homogenate was used to generate a viabl ...[more]