Ontology highlight
ABSTRACT:
SUBMITTER: Bianconi M
PROVIDER: S-EPMC5122335 | biostudies-literature | 2016 Jun
REPOSITORIES: biostudies-literature
Bianconi Maristella M Faloppi Luca L Loretelli Cristian C Zizzi Antonio A Giampieri Riccardo R Bittoni Alessandro A Andrikou Kalliopi K Del Prete Michela M Burattini Luciano L Montironi Rodolfo R Scartozzi Mario M Cascinu Stefano S
Oncotarget 20160601 25
<h4>Introduction</h4>Recent data from the COMPARZ study seem to suggest a non-inferiority of pazopanib confronted with sunitinib in PFS and OS. We previously reported how VEGF and VEGFR polymorphisms might have a predictive role in patients treated with first-line sunitinib. Aim of our study was to investigate whether tumour angiogenesis genotyping could influence clinical outcome in RCC patients treated with either sunitinib or pazopanib, in order to help clinicians select the appropriate treat ...[more]