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Ocular Neuromyotonia Associated with Chronic Inflammatory Demyelinating Polyneuropathy.


ABSTRACT: Ocular neuromyotonia (ONM) is a neuro-ophthalmic disorder characterized by episodic diplopia caused by contraction of one or more ocular muscles due to spontaneous excitation of the respective ocular motor nerve. We report a patient whose ocular neuromyotonia arose in the setting of a subacute demyelinating polyneuropathy consistent with chronic inflammatory demyelinating polyneuropathy (CIDP) and subsequently resolved following the initiation of intravenous immunoglobulin (IVIg) for her neuropathy. Our patient provides additional evidence towards the role of demyelination and ephaptic neurotransmission in ocular neuromyotonia and also represents the first reported case of ocular neuromyotonia associated with a systemic neurological condition.

SUBMITTER: Kung NH 

PROVIDER: S-EPMC5123132 | biostudies-literature | 2015 Oct

REPOSITORIES: biostudies-literature

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Ocular Neuromyotonia Associated with Chronic Inflammatory Demyelinating Polyneuropathy.

Kung Nathan H NH   Bucelli Robert C RC   McClelland Collin M CM   Van Stavern Gregory P GP  

Neuro-ophthalmology (Aeolus Press) 20150824 5


Ocular neuromyotonia (ONM) is a neuro-ophthalmic disorder characterized by episodic diplopia caused by contraction of one or more ocular muscles due to spontaneous excitation of the respective ocular motor nerve. We report a patient whose ocular neuromyotonia arose in the setting of a subacute demyelinating polyneuropathy consistent with chronic inflammatory demyelinating polyneuropathy (CIDP) and subsequently resolved following the initiation of intravenous immunoglobulin (IVIg) for her neuropa  ...[more]

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