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CHD associated with syndromic diagnoses: peri-operative risk factors and early outcomes.

ABSTRACT: CHD is frequently associated with a genetic syndrome. These syndromes often present specific cardiovascular and non-cardiovascular co-morbidities that confer significant peri-operative risks affecting multiple organ systems. Although surgical outcomes have improved over time, these co-morbidities continue to contribute substantially to poor peri-operative mortality and morbidity outcomes. Peri-operative morbidity may have long-standing ramifications on neurodevelopment and overall health. Recognising the cardiovascular and non-cardiovascular risks associated with specific syndromic diagnoses will facilitate expectant management, early detection of clinical problems, and improved outcomes--for example, the development of syndrome-based protocols for peri-operative evaluation and prophylactic actions may improve outcomes for the more frequently encountered syndromes such as 22q11 deletion syndrome.

SUBMITTER: Landis BJ

PROVIDER: S-EPMC5125077 | biostudies-literature | 2016 Jan

REPOSITORIES: biostudies-literature

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CHD associated with syndromic diagnoses: peri-operative risk factors and early outcomes.

Landis Benjamin J BJ Cooper David S DS Hinton Robert B RB

Cardiology in the young 20150908 1

CHD is frequently associated with a genetic syndrome. These syndromes often present specific cardiovascular and non-cardiovascular co-morbidities that confer significant peri-operative risks affecting multiple organ systems. Although surgical outcomes have improved over time, these co-morbidities continue to contribute substantially to poor peri-operative mortality and morbidity outcomes. Peri-operative morbidity may have long-standing ramifications on neurodevelopment and overall health. Recogn ...[more]

PMID: 26345374

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Dataset Information

CHD associated with syndromic diagnoses: peri-operative risk factors and early outcomes.

Publications

CHD associated with syndromic diagnoses: peri-operative risk factors and early outcomes.

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